Publications

2024

Kraav J, Zagura M, Viitasalo A, Soininen S, Veijalainen A, Kähönen M, Jürimäe J, Tillmann V, Haapala E, Lakka T. Associations of Cardiovascular Health Metrics in Childhood and Adolescence With Arterial Health Indicators in Adolescence: The PANIC Study. J Am Heart Assoc 2024 (in press). doi: 10.1161/JAHA.124.035790.

Haapala EA, Leppänen MH, Skog H, Lubans DR, Viitasalo A, Lintu N, Jalanko P, Määttä S, Lakka TA. Childhood Physical Fitness as a Predictor of Cognition and Mental Health in Adolescence: The PANIC Study. Sports Med. 2024 Sep 10. doi: 10.1007/s40279-024-02107-z.

Zarei I, Eloranta AM, Klåvus A, Väistö J, Lehtonen M, Mikkonen S, Koistinen VM, Sallinen T, Haapala EA, Lintu N, Soininen S, Haikonen R, Atalay M, Schwab U, Auriola S, Kolehmainen M, Hanhineva K, Lakka TA. Eight-year diet and physical activity intervention affects serum metabolites during childhood and adolescence: A nonrandomized controlled trial. iScience 2024;27(7):110295. doi: 10.1016/j.isci.2024.110295.

Healy DR, Zarei I, Mikkonen S, Soininen S, Viitasalo A, Haapala EA, Auriola S, Hanhineva K, Kolehmainen M, Lakka TA. Longitudinal associations of an exposome score with serum metabolites from childhood to adolescence. Commun Biol 2024;7(1):890. doi: 10.1038/s42003-024-06146-0.

Skog HM, Määttä S, Säisänen L, Lakka TA, Haapala EA. Associations of physical fitness with cortical inhibition and excitation in adolescents and young adults. Front Neurosci 2024;18:1297009. doi: 10.3389/fnins.2024.1297009.

Gonçalves Soares A, Santos S, Seyve E, Nedelec R, Puhakka S, Eloranta AM, Mikkonen S, Yuan WL, Lawlor DA, Heron J, Vrijheid M, Lepeule J, Nieuwenhuijsen M, Fossati S, Jaddoe VWV, Lakka T, Sebert S, Heude B, Felix JF, Elhakeem A, Timpson NJ. Prenatal Urban Environment and Blood Pressure Trajectories From Childhood to Early Adulthood. JACC Adv. 2024 Jan 8;3(2):100808. doi: 10.1016/j.jacadv.2023.100808.

Jalanko P, Bond B, Laukkanen JA, Brage S, Ekelund U, Laitinen T, Määttä S, Kähönen M, Haapala EA, Lakka TA. Association between arterial health and cognition in adolescents: The PANIC study. Physiol Rep 2024;12(9):e16024. doi: 10.14814/phy2.16024.

Toivonen E, Lee E, Leppänen MH, Laitinen T, Kähönen M, Lakka TA, Haapala EA. The associations of depressive symptoms and perceived stress with arterial health in adolescents. Physiol Rep 2024;12(6):e15986. doi: 10.14814/phy2.15986.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10959692/pdf/PHY2-12-e15986.pdf

Haapala EA, Leppänen MH, Lee E, Savonen K, Laukkanen JA, Kähönen M, Brage S, Lakka TA. Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence. J Am Heart Assoc 2024;13(6):e031837. doi: 10.1161/JAHA.123.031837.

de Ruyter H, Aitokari L, Lahti S, Huhtala H, Lakka TA, Laivuori H, Kurppa K. Maternal gestational hypertension, smoking and pre-eclampsia are associated with metabolic dysfunction-associated fatty liver disease in offspring with overweight. Acta Obstet Gynecol Scand 2024 (in press). doi: 10.1111/aogs.14816.

Liimatta J, Jääskeläinen J, Mäntyselkä A, Häkkinen MR, Auriola S, Voutilainen R, Flück CE, Lakka TA. Accelerated Early Childhood Growth Is Associated With the Development of Earlier Adrenarche and Puberty. J Endocr Soc 2024;8(4):bvae026. doi: 10.1210/jendso/bvae026.

Skinner AM, Barker AR, Moore SA, Soininen S, Haapala EA, Väistö J, Westgate K, Brage S, Lakka TA, Vlachopoulos D. Cross-sectional and longitudinal associations between the 24-hour movement behaviours, including muscle and bone strengthening activity, with bone and lean mass from childhood to adolescence. BMC Public Health. 2024 Jan 19;24(1):227. doi: 10.1186/s12889-024-17711-x.

Aitokari L, Lahti S, Kivelä L, Riekki H, Hiltunen P, Vuorela N, Viitasalo A, Soininen S, Huhtala H, Lakka TA, Kurppa K. Alanine Aminotransferase Cutoffs for the Pediatric Fatty Liver Disease: Major Impact of the Reference Population. J Pediatr Gastroenterol Nutr 2024;78(3):488-496. http://doi.org/10.1002/jpn3.12040.

Jalanko P, Säisänen L, Kallioniemi E, Könönen M, Lakka TA, Määttä S, Haapala EA. Associations between physical fitness and cerebellar gray matter volume in adolescents. Scand J Med Sci Sports 2024;34(1):e14513. doi: 10.1111/sms.14513.

2023

Laamanen SE, Eloranta AM, Haapala EA, Sallinen T, Schwab U, Lakka TA. Associations of diet quality and food consumption with serum biomarkers for lipid and amino acid metabolism in Finnish children: the PANIC study. Eur J Nutr. 2023 Dec 21. doi: 10.1007/s00394-023-03293-8.

Naveed S, Sallinen T, Eloranta AM, Skog H, Jalkanen H, Brage S, Ekelund U, Pentikäinen H, Savonen K, Lakka TA, Haapala EA. Effects of 2-year dietary and physical activity intervention on cognition in children-a nonrandomized controlled trial. Scand J Med Sci Sports. 2023. doi: 10.1111/sms.14464.

Beaumont RN, Flatley C, Vaudel M, Wu X, Chen J, Moen GH, Skotte L, Helgeland Ø, Solé-Navais P, Banasik K, Albiñana C, Ronkainen J, Fadista J, Stinson SE, Trajanoska K, Wang CA, Westergaard D, Srinivasan S, Sánchez-Soriano C, Bilbao JR, Allard C, Groleau M, Kuulasmaa T, Leirer DJ, White F, Jacques PÉ, Cheng H, Hao K, Andreassen OA, Åsvold BO, Atalay M, Bhatta L, Bouchard L, Brumpton BM, Brunak S, Bybjerg-Grauholm J, Ebbing C, Elliott P, Engelbrechtsen L, Erikstrup C, Estarlich M, Franks S, Gaillard R, Geller F, Grove J, Hougaard DM, Kajantie E, Morgen CS, Nohr EA, Nyegaard M, Palmer CNA, Pedersen OB; Early Growth Genetics (EGG) Consortium; Rivadeneira F, Sebert S, Shields BM, Stoltenberg C, Surakka I, Thørner LW, Ullum H, Vaarasmaki M, Vilhjalmsson BJ, Willer CJ, Lakka TA, Gybel-Brask D, Bustamante M, Hansen T, Pearson ER, Reynolds RM, Ostrowski SR, Pennell CE, Jaddoe VWV, Felix JF, Hattersley AT, Melbye M, Lawlor DA, Hveem K, Werge T, Nielsen HS, Magnus P, Evans DM, Jacobsson B, Järvelin MR, Zhang G, Hivert MF, Johansson S, Freathy RM, Feenstra B, Njølstad PR. Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nat Genet. 2023 Nov;55(11):1807-1819. doi: 10.1038/s41588-023-01520-w.

Medina-Gomez C, Mullin BH, Chesi A, Prijatelj V, Kemp JP, Shochat-Carvalho C, Trajanoska K, Wang C, Joro R, Evans TE, Schraut KE, Li-Gao R, Ahluwalia TS, Zillikens MC, Zhu K, Mook-Kanamori DO, Evans DS, Nethander M, Knol MJ, Thorleifsson G, Prokic I, Zemel B, Broer L, McGuigan FE, van Schoor NM, Reppe S, Pawlak MA, Ralston SH, van der Velde N, Lorentzon M, Stefansson K, Adams HHH, Wilson SG, Ikram MA, Walsh JP, Lakka TA, Gautvik KM, Wilson JF, Orwoll ES, van Duijn CM, Bønnelykke K, Uitterlinden AG, Styrkársdóttir U, Akesson KE, Spector TD, Tobias JH, Ohlsson C, Felix JF, Bisgaard H, Grant SFA, Richards JB, Evans DM, van der Eerden B, van de Peppel J, Ackert-Bicknell C, Karasik D, Kague E, Rivadeneira F. Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis. Commun Biol. 2023 Jul 4;6(1):691. doi: 10.1038/s42003-023-04869-0.

Nguyen DTA, Julkunen P, Säisänen L, Määttä S, Rissanen SM, Lintu N, Könönen M, Lakka T, Karjalainen PA. Developmental models of motor-evoked potential features by transcranial magnetic stimulation across age groups from childhood to adulthood. Sci Rep. 2023 Jun 30;13(1):10604. doi: 10.1038/s41598-023-37775-w.

Liimatta J, Flück CE, Mäntyselkä A, Häkkinen MR, Auriola S, Voutilainen R, Jääskeläinen J, Lakka TA. Effects of 2-year physical activity and dietary intervention on adrenarchal and pubertal development: the PANIC study. J Clin Endocrinol Metab. 2023. doi: 10.1210/clinem/dgad367.

Räsänen K, Markula-Patjas K, Kantanen S, Sipilä K, Lakka TA,  Arikoski P, Piippo-Savolainen E. Impaired cardiorespiratory and neuromuscular fitness in children and adolescents with juvenile idiopathic arthritis: a cross-sectional case-control study in the era of biologic drug therapies. Pediatr Rheumatol Online J 2023;21(1):26. doi: 10.1186/s12969-023-00808-9.

Haapala EA, Widlund A, Poikkeus AM, Lima RA, Brage S, Aunio P, Lakka TA. Cross-lagged associations between physical activity, motor performance, and academic skills in primary-school children.  Med Sci Sports Exerc 2023. doi: 10.1249/MSS.0000000000003163.

Virkkala V, Eloranta AM, Suominen AL, Vierola A, Ikävalko T, Väistö J, Mikkonen S, Methuen M, Schwab U, Viljakainen H, Leinonen J, Närhi M, Lakka TA. Associations of diet quality, food consumption, eating frequency, and eating behaviour with dental caries experience in Finnish children: A 2-year longitudinal study. Br J Nutr 2023;129:1415-1425. doi: 10.1017/S0007114522002550.

Saner C, Senior AM, Zhang H, Eloranta A-M, Magnussen CG, Sabin MA, Juonala M, Janner M, Burgner D, Schwab U, Haapala EA, Heitmann BL, Simpson SJ, Raubenheimer D, Lakka TA. Evidence for protein leverage in a population sample of children and adolescents. Eur J Clin Nutr 2023. Online ahead of print. doi: 10.1038/s41430-023-01276-w. 

Haapala EA, Kuronen E, Ihalainen JK, Lintu N, Leppänen MH, Tompuri T, Atalay M, Schwab U, Lakka TA. Cross-sectional associations between physical fitness and biomarkers of inflammation in children – the PANIC Study. Scand J Med Sci Sports 2023;33:1000-1009.  doi: 10.1111/sms.14337.

Ortega FB, Leskošek B, Blagus R, Gil-Cosano JJ, Mäestu J, Tomkinson GR, Ruiz JR, Mäestu E, Starc G, Milanovic I, Tammelin TH, Sorić M, Scheuer C, Carraro A, Kaj M, Csányi T, Sardinha LB, Lenoir M, Emeljanovas A, Mieziene B, Sidossis LS, Pihu M, Lovecchio N, Konstabel K, Tambalis KD, Štefan L, Drenowatz C, Rubín L, Gontarev S, Castro-Piñero J, Vanhelst J, O’Keeffe B, Veiga OL, Gisladottir T, Sandercock G, Misigoj-Durakovic M, Niessner C, Riso EM, Popovic S, Kuu S, Chinapaw M, Clavel I, Labayen I, Dobosz J, Colella D, Kriemler S, Salaj S, Noriega MJ, Bös K, Sánchez-López M, Lakka TA, Tabacchi G, Novak D, Ahrens W, Wedderkopp N, Jurak G; FitBack, HELENA and IDEFICS consortia. European fitness landscape for children and adolescents: updated reference values, fitness maps and country rankings based on nearly 8 million test results from 34 countries gathered by the FitBack network. Br J Sports Med 2023;57(5):299-310. doi: 10.1136/bjsports-2022-106176.

Skinner AM, Vlachopoulos D, Barker AR, Moore SA, Rowlands AV, Soininen S, Haapala EA, Väistö J, Westgate K, Brage S, Lakka TA. Physical activity volume and intensity distribution in relation to bone, lean and fat mass in children. Scand J Med Sci Sports 2023;33:267–282. doi: 10.1111/sms.14255.

Soininen S, Eloranta AM, Schwab U, Lakka TA. Sources of vitamin D and determinants of serum 25-hydroxyvitamin D in Finnish adolescents. Eur J Nutr 2023;62(2):1011-1025. doi: 10.1007/s00394-022-03039-y.

2022

Haapala EA, Leppänen MH, Lehti M, Lintu N, Tompuri T, Viitasalo A, Schwab U, Lakka TA. Cross-sectional associations between cardiorespiratory fitness and NMR-derived metabolic biomarkers in children – the PANIC study. Front Endocrinol 2022;1313:954418. https://doi.org/10.3389/fendo.2022.954418.

Methuen M, Kangasmaa H, Alaraudanjoki V, Suominen AL, Anttonen V, Vähänikkilä H, Karjalainen P, Väistö J, Lakka T, Laitala ML. Prevalence of erosive tooth wear and associated dietary factors among a group of Finnish adolescents. Caries Research 2022;56(5-6):477-487. https://doi.org/10.1159/000527305.

Haapala EA, Tompuri T, Lintu N, Viitasalo A, Savonen K, Lakka TA, Laukkanen JA. Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults? J Sci Med Sport. 2022 Aug 4:S1440-2440(22)00213-4. doi: 10.1016/j.jsams.2022.08.002. 

Lima RA, Soares FC, van Poppel M, Savinainen S, Mäntyselkä A, Haapala EA, Lakka T. Determinants of Cognitive Performance in Children and Adolescents: A Populational Longitudinal Study. Int J Environ Res Public Health. 2022 Jul 23;19(15):8955. doi: 10.3390/ijerph19158955.

Sallinen T, Viitasalo A, Lintu N, Väistö J, Soininen S, Jalkanen H, Haapala EA, Mikkonen S, Schwab U, Lakka TA, Eloranta AM. The effects of an 8-year individualised lifestyle intervention on food consumption and nutrient intake from childhood to adolescence: the PANIC Study. J Nutr Sci. 2022 Jun 2;11:e40. doi: 10.1017/jns.2022.13.

Vogelezang S, Bradfield JP; Early Growth Genetics Consortium, Grant SFA, Felix JF, Jaddoe VWV. Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes. BMC Med Genomics. 2022 Jun 4;15(1):124. doi: 10.1186/s12920-022-01281-1.

Koskivuori J, Voutilainen R, Uusitalo L, Lehtonen M, Lakka T, Auriola S, Häkkinen MR. A quantitative ultra-performance liquid chromatography high-resolution mass spectrometry analysis of steroids from human scalp hair. J Pharm Biomed Anal 2022;215:114768. doi: 10.1016/j.jpba.2022.114768.

Constable AM, Vlachopoulos D, Barker AR, Moore SA, Soininen S, Haapala EA, Väistö J, Jääskeläinen J, Voutilainen R, Auriola S, Häkkinen MR, Laitinen T, Lakka TA. The Mediating Role of Endocrine Factors in the Positive Relationship Between Fat Mass and Bone Mineral Content in Children Aged 9–11 Years: The Physical Activity and Nutrition in Children Study. Front Endocrinol 2022. doi: 10.3389/fendo.2022.850448.

Ronkainen J, Nedelec R, Atehortua A, Balkhiyarova Z, Cascarano A, Ngoc Dang V, Elhakeem A, van Enckevort E, Goncalves Soares A, Haakma S, Halonen M, Heil K, Heiskala A, Hyde E, Jacquemin B, Keikkala E, Kerckhoffs J, Klåvus A, Kopinska JA, Lepeule J, Marazzi F, Motoc I, Näätänen M, Ribbenstedt A, Rundblad A, Savolainen O, Simonetti V, de Toro Eadie N, Tzala E, Ulrich A, Wright T, Zarei I, d’Amico E, Belotti F, Brunius C, Castleton C, Charles MA, Gaillard R, Hanhineva K, Hoek G, Holven KB, Jaddoe VWV, Kaakinen M, Kajantie E, Kavousi M, Lakka T, Matthews J, Piano Mortari A, Vääräsmäki M, Voortman T, Webster C, Zins M, Atella V, Bulgheroni M, Chadeau-Hyam M, Conti G, Evans J, Felix JF, Heude B, Järvelin MR, Kolehmainen M, Landberg R, Lekadir K, Parusso S, Prokopenko I, de Rooij SR, Roseboom T, Swertz M, Timpson N, Ulven SM, Vermeulen R, Juola T, Sebert S. LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases. Environ Epidem 2022;6(1):e184. doi: 10.1097/EE9.0000000000000184. eCollection 2022

Leppänen MH, Haapala EA, Väistö J, Ekelund U, Brage U, Kilpeläinen TO, Lakka TA. Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk. Scand J Med Sci Sports 2022; 32(1):255-266. doi: 10.1111/sms.14081.

2021

Kuvaja-Köllner V, Lintu N, Lindi V, Rissanen E, Eloranta AM, Kiiskinen S, Martikainen J,  Kankaanpää E, Valtonen H, Lakka TA. Cost-effectiveness of physical activity intervention in children – results based on the Physical Activity and Nutrition in Children (PANIC) study. Int J Behav Nutr Phys Act 2021;18:116. doi: 10.1186/s12966-021-01181-0.

Methuen M, Kauppinen S, Suominen AL, Eloranta AM, Väistö J, Lakka T, Vähänikkilä H, Anttonen V. Dental caries among Finnish teenagers participating in physical activity and diet intervention: association with anthropometrics and behavioural factors. BMC Oral Health 2021;21(1):333. doi: 10.1186/s12903-021-01690-1.

Constable AM, Porter JE, Benger D, Vlachopoulos D, Barker AR, Moore SA, Soininen S, Haapala EA, Westgate K, Brage S, Agostinete RR, Fernandes RA, Lakka TA. The positive relationship between moderate-to-vigorous physical activity and bone mineral content is not mediated by free leptin index in prepubertal children: The PANIC study. Int J Environ Res Public Health 2021;18(10):5365. doi: 10.3390/ijerph18105365.

Korhonen M, Väistö J, Veijalainen A, Leppänen M, Ekelund U, Laukkanen JA, Brage S, Lintu N, Haapala EA, Lakka TA. Longitudinal associations of physical activity, sedentary time, and cardiorespiratory fitness with arterial health in children – the PANIC study. J Sports Sci. 2021; 391980-1987. doi: 10.1080/02640414.2021.1912450.

Constable AM, Vlachopoulos D, Barker AR, Moore SA, Soininen S, Haapala EA, Väistö J, Westgate K, Brage S, Mahonen A, Lakka TA. The independent and interactive associations of physical activity intensity and vitamin D status with bone mineral density in prepubertal children: The PANIC Study. Osteoporos Int 2021;32:1609-1620. doi: 10.1007/s00198-021-05872-z.

Haapala EA, Väistö J, Ihalainen JK, González CT, Leppänen MH, Veijalainen A, Sallinen T, Eloranta AM, Ekelund U, Schwab U, Brage S,  Atalay M, Lakka TA. Associations of physical activity, sedentary time, and diet quality with biomarkers of inflammation in children. Eur J Sport Sci 2022;22(6):906-915. doi: 10.1080/17461391.2021.1892830. Epub 2021.

Haapala EA, Gao Y, Lintu N, Väistö J, Vanhala A, Tompuri T, Lakka TA, Finni T. Associations between cardiorespiratory fitness, motor competence, and adiposity in children. Transl Sports Med 2021;4:56-64. https://doi.org/10.1002/tsm2.198

2020

Vogelezang S, Bradfield JP, Ahluwalia TS, Curtin JA, Lakka TA, Grarup N, Scholz M, van der Most PJ, Monnereau C, Stergiakouli E, Heiskala A, Horikoshi M, Fedko IO, Vilor-Tejedor N, Cousminer DL, Standl M, Wang CA, Viikari J, Geller F, Íñiguez C, Pitkänen N, Chesi A, Bacelis J, Yengo L, Torrent M, Ntalla I, Helgeland Ø, Selzam S, Vonk JM, Zafarmand MH, Heude B, Farooqi IS, Alyass A, Beaumont RN, Have CT, Rzehak P, Bilbao JR, Schnurr TM, Barroso I, Bønnelykke K, Beilin LJ, Carstensen L, Charles MA, Chawes B, Clément K, Closa-Monasterolo R, Custovic A, Eriksson JG, Escribano J, Groen-Blokhuis M, Grote V, Gruszfeld D, Hakonarson H, Hansen T, Hattersley AT, Hollensted M, Hottenga JJ, Hyppönen E, Johansson S, Joro R, Kähönen M, Karhunen V, Kiess W, Knight BA, Koletzko B, Kühnapfel A, Landgraf K, Langhendries JP, Lehtimäki T, Leinonen JT, Li A, Lindi V, Lowry E, Bustamante M, Medina-Gomez C, Melbye M, Michaelsen KF, Morgen CS, Mori TA, Nielsen TRH, Niinikoski H, Oldehinkel AJ, Pahkala K, Panoutsopoulou K, Pedersen O, Pennell CE, Power C, Reijneveld SA, Rivadeneira F, Simpson A, Sly PD, Stokholm J, Teo KK, Thiering E, Timpson NJ, Uitterlinden AG, van Beijsterveldt CEM, van Schaik BDC, Vaudel M, Verduci E, Vinding RK, Vogel M, Zeggini E, Sebert S, Lind MV, Brown CD, Santa-Marina L, Reischl E, Frithioff-Bøjsøe C, Meyre D, Wheeler E, Ong K, Nohr EA, Vrijkotte TGM, Koppelman GH, Plomin R, Njølstad PR, Dedoussis GD, Froguel P, Sørensen TIA, Jacobsson B, Freathy RM, Zemel BS, Raitakari O, Vrijheid M, Feenstra B, Lyytikäinen LP, Snieder H, Kirsten H, Holt PG, Heinrich J, Widén E, Sunyer J, Boomsma DI, Järvelin MR, Körner A, Davey Smith G, Holm JC, Atalay M, Murray C, Bisgaard H, McCarthy MI; Early Growth Genetics Consortium, Jaddoe VWV, Grant SFA, Felix JF. Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. PLoS Genet 2020;16(10):e1008718 . doi: 10.1371/journal.pgen.1008718.

Lakka TA, Lintu N, Väistö J, Viitasalo A, Sallinen T, Haapala EA, Tompuri TT, Soininen S, Karjalainen P, Schnurr TM, Mikkonen S, Atalay M, Kilpeläinen TO, Laitinen T, Laaksonen DE, Savonen K, Brage S, Schwab U, Jääskeläinen J, Lindi V, Eloranta AM. A 2-year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC study. Diabetologia 2020;63:2270-2281. doi: 10.1007/s00125-020-05250-0.

Eloranta AM, Sallinen T, Viitasalo A, Lintu N, Väistö J, Jalkanen H, Tompuri TT, Soininen S, Haapala EA, Kiiskinen S, Schnurr TM, Kilpeläinen TO, Mikkonen S, Savonen K, Atalay M, Brage S, Laaksonen DE, Lindi V, Ågren J, Schwab U, Jääskeläinen J, Lakka TA. The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study.  Eur J Nutr 2020;10.1007/s00394-020-02260-x. doi:10.1007/s00394-020-02260-x.

Naveed S, Lakka T, Haapala EA. An overview on the associations between health behaviors and brain health in children and adolescents with special reference to diet quality. Int J Environ Res Public Health 2020;17(3):953.  doi: 10.3390/ijerph17030953. Review.

Savinainen S, Viitasalo A, Sallinen T, Jääskeläinen J, Lakka TA. Child-related and parental predictors for thelarche in a general population of girls: the PANIC study. Pediatr Res 2020;88:676-680. doi: 10.1038/s41390-020-0802-0.

Naveed S, Venäläinen T, Eloranta AM, Erkkilä AT, Jalkanen H, Lindi V, Lakka TA, Haapala EA. Associations of dietary carbohydrate and fatty acid intakes with cognition among children. Public Health Nutr 2020;23:1657-1663. doi: 10.1017/S1368980019003860.

Leppänen MH, Haapala EA, Veijalainen A, Seppälä S, Oliveira RS, Lintu N, Laitinen T, Tarvainen MP, Lakka TA. Associations of cardiometabolic risk factors with heart rate variability in 6–8-year-old children: the PANIC Study. Pediatr Diabetes 2020;21(2):251-258. doi: 10.1111/pedi.12967.

Rantala E, Martikainen J, Lakka T, Vanhatalo S, Heiskanen J, Väistö J, Leväsluoto J, Hassinen M, Eloranta AM, Sigfrids A, Harjumaa M. Suomalaisten lasten ja nuorten ruokaympäristö ja toimenpide-ehdotukset sen kehittämiseen terveyttä edistäväksi. Valtioneuvoston selvitys- ja tutkimustoiminnan julkaisusarja 2020:19.

Rantala E, Martikainen J, Lakka T, Harjumaa M. Tulevaisuuden säästöt tehdään nyt: huomio lasten ja nuorten ruokaympäristöön. Future savings are accomplished today – focus on food environment of children and adolescents. Policy Brief. Article Series of Government’s analysis, assessment and research activities 2020:9.

2019

Haapala EA, Wiklund P, Lintu N, Tompuri T, Väistö J, Finni T, Tarkka IM, Kemppainen T, Barker AR, Ekelund U, Brage S, Lakka TA. Cardiorespiratory fitness, physical activity, and insulin resistance in children. Med Sci Sports Exerc 2020;52(5):1144-1152. doi: 10.1249/MSS.0000000000002216.

Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, Taal HR, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, Thiering E, Timpson NJ, Bond TA, Lowry E, Brown CD, Estivill X, Lindi V, Bradfield JP, Geller F, Speed D, Coin LJM, Loh M, Barton SJ, Beilin LJ, Bisgaard H, Bønnelykke K, Alili R, Hatoum IJ, Schramm K, Cartwright R, Charles MA, Salerno V, Clément K, Claringbould AAJ; BIOS Consortium, van Duijn CM, Moltchanova E, Eriksson JG, Elks C, Feenstra B, Flexeder C, Franks S, Frayling TM, Freathy RM, Elliott P, Widén E, Hakonarson H, Hattersley AT, Rodriguez A, Banterle M, Heinrich J, Heude B, Holloway JW, Hofman A, Hyppönen E, Inskip H, Kaplan LM, Hedman AK, Läärä E, Prokisch H, Grallert H, Lakka TA, Lawlor DA, Melbye M, Ahluwalia TS, Marinelli M, Millwood IY, Palmer LJ, Pennell CE, Perry JR, Ring SM, Savolainen MJ, Rivadeneira F, Standl M, Sunyer J, Tiesler CMT, Uitterlinden AG, Schierding W, O’Sullivan JM, Prokopenko I, Herzig KH, Smith GD, O’Reilly P, Felix JF, Buxton JL, Blakemore AIF, Ong KK, Jaddoe VWV, Grant SFA, Sebert S, McCarthy MI, Järvelin MR; Early Growth Genetics (EGG) Consortium. GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Sci Adv 2019;5(9):eaaw3095. doi: 10.1126/sciadv.aaw3095.

Veijalainen A, Haapala EA, Väistö J, Leppänen MH, Lintu N, Tompuri T, Seppälä S, Ekelund U, Tarvainen MP, Westgate K, Brage S, Lakka TA. Associations of physical activity, sedentary time, and cardiorespiratory fitness with heart rate variability in 6–9-year-old children: the PANIC Study. Eur J Appl Physiol 2019;119:2487-2498. doi: 10.1007/s00421-019-04231-5.

Viitasalo A, Schnurr TM, Pitkänen N, Hollensted M, Nielsen TRH, Pahkala K, Atalay M, Lind MV, Heikkinen S, Frithioff-Bøjsøe C, Fonvig CE, Grarup N, Kähönen M, Carrasquilla GD, Larnkjaer A, Pedersen O, Michaelsen KF, Lakka TA, Holm JC, Lehtimäki T, Raitakari O, Hansen T, Kilpeläinen TO. Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis. Am J Clin Nutr 2019;110:1079-1087. doi: 10.1093/ajcn/nqz187.

Mäntyselkä A, Haapala EA, Lindi V, Häkkinen MR, Auriola S, Jääskeläinen J, Lakka TA. Associations of IGF-1 and adrenal androgens with cognition in childhood. Horm Res Paediatr 2019;91:329-335. doi: 10.1159/000501719.

Middeldorp CM, Felix JF, Mahajan A, EArly Genetics Lifecourse Epidemiology (EAGLE) consortium, Early Growth Genetics (EGG) consortium, McCarthy MI. The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects. Eur J Epidemiol 2019;34:279–300. https://doi.org/10.1007/s10654-019-00502-9.

Viitasalo A, Schnurr TM, Pitkänen N, Hollensted M, Nielsen TRH, Pahkala K, Lintu N, Lind MV, Atalay M, Frithioff-Bøjsøe C, Fonvig CE, Grarup N, Kähönen M, Larnkjaer A, Pedersen O, Holm JC, Michaelsen KF, Lakka TA, Lehtimäki T, Raitakari O, Hansen T, Kilpeläinen TO. Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents. Int J Obes (Lond) 2019; 43:2007-2016. doi: 10.1038/s41366-019-0414-0.

Bradfield JP, Vogelezang S, Felix JF, Chesi A, Helgeland Ø, Horikoshi M, Karhunen V, Lowry E, Cousminer DL, Ahluwalia TS, Thiering E, Boh ET, Zafarmand MH, Vilor-Tejedor N, Wang CA, Joro R, Chen Z, Gauderman WJ, Pitkänen N, Parra EJ, Fernandez-Rhodes L, Alyass A, Monnereau C, Curtin JA, Have CT, McCormack SE, Hollensted M, Frithioff-Bøjsøe C, Valladares-Salgado A, Peralta-Romero J, Teo YY, Standl M, Leinonen JT, Holm JC, Peters T, Vioque J, Vrijheid M, Simpson A, Custovic A, Vaudel M, Canouil M, Lindi V, Atalay M, Kähönen M, Raitakari OT, van SchaikBDC, Berkowitz RI, Cole SA, Voruganti VS, Wang Y, Highland HM, Comuzzie AG, Butte NF, Justice AE, Gahagan S, Blanco E, Lehtimäki T, Lakka TA, Hebebrand J, Bonnefond A, Grarup N, Froguel P, Lyytikäinen LP, Cruz M, Kobes S, Hanson RL, Zemel BS, Hinney A, Teo KK, Meyre D, North KE, Gilliland FD, Bisgaard H, Bustamante M, Bonnelykke K, Pennell CE, Rivadeneira F, Uitterlinden AG, Baier LJ, Vrijkotte TGM, Heinrich J, Sørensen TIA, Saw SM, Pedersen O, Hansen T, Eriksson J, Widén E, McCarthy MI, Njølstad PR, Power C, Hyppönen E, Sebert S, Brown CD, Järvelin MR, Timpson NJ, Johansson S, Hakonarson H, Jaddoe VWV, Grant SFA; Early Growth Genetics Consortium. A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity. Hum Mol Genet 2019; 28:3327-3338. doi: 10.1093/hmg/ddz161.

Tompuri TT, Jääskeläinen J, Lindi V, Laaksonen DE, Eloranta AM, Viitasalo A, Laitinen T, Lakka TA. Adiposity Criteria in Assessing Increased Cardiometabolic Risk in Prepubertal Children.  Front Endocrinol (Lausanne). 2019 Jun 26;10:410. doi: 10.3389/fendo.2019.00410. eCollection 2019.

Lakka TA, Talvia S, Sääkslahti A, Haapala EA. Fyysinen aktiivisuus ja ravitsemus lasten terveyden edistämisessä – tavoitteena lihavuuden, tyypin 2 diabeteksen ja valtimotautien ehkäisy.  In: Pietilä A-M & Terkamo-Moisio A (Ed.) Näkökulmia terveyteen ja sen edistämiseen. Publications of the University of Eastern Finland. General Series 2019; 133-166.

Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, Qiao Z, Moen GH, Vaudel M, Marsit CJ, Chen J, Nodzenski M, Schnurr TM, Zafarmand MH, Bradfield JP, Grarup N, Kooijman MN, Li-Gao R, Geller F, Ahluwalia TS, Paternoster L, Rueedi R, Huikari V, Hottenga JJ, Lyytikäinen LP, Cavadino A, Metrustry S, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Vilor-Tejedor N, Joshi PK, Painter JN, Ntalla I, Myhre R, Pitkänen N, van Leeuwen EM, Joro R, Lagou V, Richmond RC, Espinosa A, Barton SJ, Inskip HM, Holloway JW, Santa-Marina L, Estivill X, Ang W, Marsh JA, Reichetzeder C, Marullo L, Hocher B, Lunetta KL, Murabito JM, Relton CL, Kogevinas M, Chatzi L, Allard C, Bouchard L, Hivert MF, Zhang G, Muglia LJ, Heikkinen J; EGG Consortium, Morgen CS, van Kampen AHC, van Schaik BDC, Mentch FD, Langenberg C, Luan J, Scott RA, Zhao JH, Hemani G, Ring SM, Bennett AJ, Gaulton KJ, Fernandez-Tajes J, van Zuydam NR, Medina-Gomez C, de Haan HG, Rosendaal FR, Kutalik Z, Marques-Vidal P, Das S, Willemsen G, Mbarek H, Müller-Nurasyid M, Standl M, Appel EVR, Fonvig CE, Trier C, van Beijsterveldt CEM, Murcia M, Bustamante M, Bonas-Guarch S, Hougaard DM, Mercader JM, Linneberg A, Schraut KE, Lind PA, Medland SE, Shields BM, Knight BA, Chai JF, Panoutsopoulou K, Bartels M, Sánchez F, Stokholm J, Torrents D, Vinding RK, Willems SM, Atalay M, Chawes BL, Kovacs P, Prokopenko I, Tuke MA, Yaghootkar H, Ruth KS, Jones SE, Loh PR, Murray A, Weedon MN, Tönjes A, Stumvoll M, Michaelsen KF, Eloranta AM, Lakka TA, van Duijn CM, Kiess W, Körner A, Niinikoski H, Pahkala K, Raitakari OT, Jacobsson B, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Montgomery GW, Campbell H, Wilson JF, Vrijkotte TGM, Vrijheid M, de Geus EJCN, Hayes MG, Kadarmideen HN, Holm JC, Beilin LJ, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Hattersley AT, Spector TD, Kähönen M, Viikari JS, Lehtimäki T, Boomsma DI, Sebert S, Vollenweider P, Sørensen TIA, Bisgaard H, Bønnelykke K, Murray JC, Melbye M, Nohr EA, Mook-Kanamori DO, Rivadeneira F, Hofman A, Felix JF, Jaddoe VWV, Hansen T, Pisinger C, Vaag AA, Pedersen O, Uitterlinden AG, Järvelin MR, Power C, Hyppönen E, Scholtens DM, Lowe WL Jr, Davey Smith G, Timpson NJ, Morris AP, Wareham NJ, Hakonarson H, Grant SFA, Frayling TM, Lawlor DA, Njølstad PR, Johansson S, Ong KK, McCarthy MI, Perry JRB, Evans DM, Freathy RM. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.  Nat Genet 2019;51:804-814. doi: 10.1038/s41588-019-0403-1.

Säisänen L, Määttä S, Julkunen P, Niskanen E, Kallioniemi E, Gröhn H, Kemppainen S, Lakka TA, Lintu N, Eloranta AM, Vanninen R, Makkonen I, Könönen M. Functional and structural asymmetry in primary motor cortex in Asperger syndrome: a navigated TMS and imaging study. Brain Topogr 2019;32:504-518. https://doi.org/10.1007/s10548-019-00704-0.

Agbaje AO, Haapala EA, Lintu N, Viitasalo A, Väistö J, Khan S, Veijalainen A, Tompuri T, Laitinen T, Lakka TA. Associations of Cardiorespiratory Fitness and Adiposity With Arterial Stiffness and Arterial Dilatation Capacity in Response to a Bout of Exercise in Children. Pediatr Exerc Sci 2019;9:1-10. doi: 10.1123/pes.2018-0145.

Määttä S, Säisänen L, Kallioniemi E, Lakka TA, Lintu N, Haapala EA, Koskenkorva P, Niskanen E, Ferreri F, Könönen M. Maturation changes the excitability and effective connectivity of the frontal lobe: A developmental TMS-EEG study. Hum Brain Mapp 2019;40:2320-2335. doi: 10.1002/hbm.24525.

Väistö J, Haapala EA, Viitasalo A, Schnurr TM, Kilpeläinen TO, Karjalainen P, Westgate K, Lakka HM, Laaksonen DE, Ekelund U, Brage S, Lakka TA. Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children. Scand J Med Sci Sports 2019;29:113-123. doi: 10.1111/sms.13315.

Agbaje AO, Haapala EA, Lintu N, Viitasalo A, Barker AR, Takken T, Tompuri T, Lindi V, Lakka TA. Peak oxygen uptake cut-points to identify children at increased cardiometabolic risk – The PANIC Study.  Scand J Med Sci Sports 2019;29:16-24.  doi: 10.1111/sms.13307.

Haapala EA, Lintu N, Väistö J, Tompuri T, Soininen S, Viitasalo A, Eloranta A-M, Venäläinen T, Sääkslahti A, Laitinen T, Lakka TA. Longitudinal associations of fitness, motor competence, and adiposity with cognition. Med Sci Sports Exerc 2019;51:465-471. doi: 10.1249/MSS.0000000000001826.

2018

Haworth S, Shungin D, van der Tas JT, Vucic S, Medina-Gomez C, Yakimov V, Feenstra B, Shaffer JR, Lee MK, Standl M, Thiering E, Wang C, Bønnelykke K, Waage J, Jessen LE, Nørrisgaard PE, Joro R, Seppälä I, Raitakari O, Dudding T, Grgic O, Ongkosuwito E, Vierola A, Eloranta AM, West NX, Thomas SJ, McNeil DW, Levy SM, Slayton R, Nohr EA, Lehtimäki T, Lakka T, Bisgaard H, Pennell C, Kühnisch J, Marazita ML, Melbye M, Geller F, Rivadeneira F, Wolvius EB, Franks PW, Johansson I, Timpson NJ. Consortium-based genome-wide meta-analysis for childhood dental caries traits. Hum Mol Genet 2018;27:3113-3127. doi: 10.1093/hmg/ddy237.

Haapala EA, Paananen J, Hiltunen M, Lakka TA. Associations of Genetic Susceptibility to Alzheimer’s Disease with Adiposity and Cardiometabolic Risk Factors among Children in a 2-Year Follow-up Study. J Alzheimers Dis 2018;64:587-595. doi: 10.3233/JAD-180216.

Mäntyselkä A, Lindi V, Viitasalo A, Eloranta AM, Ågren J, Väisänen S, Voutilainen R, Laitinen T, Lakka TA, Jääskeläinen J. Associations of Dehydroepiandrosterone Sulfate With Cardiometabolic Risk Factors in Prepubertal Children. J Clin Endocrinol Metab 2018;103:2592-2600. doi: 10.1210/jc.2018-00184.

Soininen S, Eloranta AM, Viitasalo A, Dion G, Erkkilä A, Sidoroff V, Lindi V, Mahonen A, Lakka TA. Serum 25-hydroxyvitamin D, Plasma Lipids, and Associated Gene Variants in Prepubertal Children. J Clin Endocrinol Metab 2018;103:2670-2679.  doi: 10.1210/jc.2018-00335.

Ikävalko T, Lehto S, Lintu N, Väistö J, Eloranta AM, Haapala EA, Vierola A, Myllykangas R, Tuomilehto H, Brage S, Pahkala R, Närhi M, Lakka TA. Health-related correlates of psychological well-being among girls and boys 6–8 years of age: The Physical Activity and Nutrition in Children study. J Paediatr Child Health 2018;54:506-509. doi: 10.1111/jpc.13891.

Haapala EA, Lintu N, Eloranta AM, Venäläinen T, Poikkeus AM, Ahonen T, Lindi V, Lakka TA. Mediating effects of motor performance, cardiorespiratory fitness, physical activity, and sedentary behaviour on the associations of adiposity and other cardiometabolic risk factors with academic achievement in children. J Sports Sci 2018;36:2296-2303. doi: 10.1080/02640414.2018.1449562.

Häkkinen MR, Heinosalo T, Saarinen N, Linnanen T, Voutilainen R, Lakka T, Jääskeläinen J, Poutanen M, Auriola S. Analysis by LC–MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue. J Pharm Biomed Anal 2018;152:165-172.

Eloranta AM, Jääskeläinen J, Venäläinen T, Jalkanen H, Kiiskinen S, Mäntyselkä A, Schwab U, Lindi V, Lakka TA. Birth weight is associated with dietary factors at the age of 6–8 years – the PANIC Study. Public Health Nutr 2018;21:1278-1285. doi: 10.1017/S1368980017004013.

Soininen S, Sidoroff V, Lindi V, Mahonen A, Kröger L, Kröger H, Jääskeläinen J, Atalay M, Laaksonen DE, Laitinen T, Lakka TA. Body fat mass, lean body mass and associated biomarkers as determinants of bone mineral density in children 6-8years of age – The Physical Activity and Nutrition in Children (PANIC) study. Bone 2018;108:106-114.

Medina-Gomez C, Kemp JP, Trajanoska K, Luan J, Chesi A, Ahluwalia TS, Mook-Kanamori DO, Ham A, Hartwig FP, Evans DS, Joro R, Nedeljkovic I, Zheng HF, Zhu K, Atalay M, Liu CT, Nethander M, Broer L, Porleifsson G, Mullin BH, Handelman SK, Nalls MA, Jessen LE, Heppe DHM, Richards JB, Wang C, Chawes B, Schraut KE, Amin N, Wareham N, Karasik D, Van der Velde N, Ikram MA, Zemel BS, Zhou Y, Carlsson CJ, Liu Y, McGuigan FE, Boer CG, Bønnelykke K, Ralston SH, Robbins JA, Walsh JP, Zillikens MC, Langenberg C, Li-Gao R, Williams FMK, Harris TB, Akesson K, Jackson RD, Sigurdsson G, den Heijer M, van der Eerden BCJ, van de Peppel J, Spector TD, Pennell C, Horta BL, Felix JF, Zhao JH, Wilson SG, de Mutsert R, Bisgaard H, Styrkársdóttir U, Jaddoe VW, Orwoll E, Lakka TA, Scott R, Grant SFA, Lorentzon M, van Duijn CM, Wilson JF, Stefansson K, Psaty BM, Kiel DP, Ohlsson C, Ntzani E, van Wijnen AJ, Forgetta V, Ghanbari M, Logan JG, Williams GR, Bassett JHD, Croucher PI, Evangelou E, Uitterlinden AG, Ackert-Bicknell CL, Tobias JH, Evans DM, Rivadeneira F. Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Am J Hum Genet 2018;102:88-102.

Mäntyselkä A, Jääskeläinen J, Eloranta A-M, Väistö J, Voutilainen R, Ong K, Brage S, Lakka TA, Lindi V. Associations of lifestyle factors with serum dehydroepiandrosterone sulfate and insulin-like growth factor-1 concentration in prepubertal children. Clin Endocrinol 2018; 88:234-242. doi: 10.1111/cen.13511.

Säisänen L, Julkunen P, Lakka T, Lindi V, Könönen M, Määttä S. Development of corticospinal motor excitability and cortical silent period from mid-childhood to adulthood – a navigated TMS study. Neurophysiol Clin 2018;48:65-75. doi: 10.1016/j.neucli.2017.11.004.

Ikävalko T, Närhi M, Eloranta A-M, Lintu N, Myllykangas R, Vierola A, Tuomilehto H, Lakka T, Pahkala R. Predictors of sleep disordered breathing in children: the PANIC study. Eur. J. Orthod. 2018;40:268-272. doi: 10.1093/ejo/cjx056.

Tompuri T, Lintu N, Laitinen T, Lakka TA. Relation of oxygen uptake to work rate in prepubertal healthy children – reference for VO2/W-slope and effect on cardiorespiratory fitness assessment. Clin. Physiol. Funct. Imaging 2018;38:645-651. doi: 10.1111/cpf.12461.

Schnurr TM, Viitasalo A, Eloranta A-M, Damsgaard CT, Mahendran Y, Have CT, Väistö J, Hjorth MF, Christensen LB, Brage S, Atalay M, Lyytikainen L-P, Lindi V, Lakka T, Michaelsen KF, Kilpelainen TO, Hansen T. Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children. Int J. Obes. 2018;42:111-114. doi: 10.1038/ijo.2017.235.

Warrington NM, Richmond R, Fenstra B, Myhre R, Gaillard R, Paternoster L, Wang CA, Beaumont RN, Das S, Murcia M, Barton SJ, Espinosa A, Thiering E, Atalay M, Pitkanen N, Ntalla I, Jonsson AE, Freathy R, Karhunen V, Tiesler CMT, Allard C, Crawford A, Ring SM, Melbye M, Magnus P, Rivadeneira F, Skotte L, Hansen T, Marsh J, Guxens M, Holloway JW, Grallert H, Jaddoe VW V, Lowe WL, Roumeliotaki T, Hattersley AT, Lindi V, Pahkala K, Panoutsopoulou K, Standl M, Flexeder C, Bouchard L, Nohr EA, Marina LS, Kogevinas M, Niinikoski H, Dedoussis G, Heinrich J, Reynolds RM, Lakka T, Zeggini E, Raitakari OT, Chatzi L, Inskip HM, Bustamante M, Hivert M-F, Jarvelin M-R, Sorensen TIA, Pennell C, Felix JF, Jacobsson B, Geller F, Evans DM, Lawlor DA. Maternal and fetal genetic contribution to gestational weight gain. Int. J. Obes. 2018;42:775-784.

2017

Collings PJ, Westgate K, Vaisto J, Wijndaele K, Atkin AJ, Haapala EA, Lintu N, Laitinen T, Ekelund U, Brage S, Lakka TA. Cross-Sectional Associations of Objectively-Measured Physical Activity and Sedentary Time with Body Composition and Cardiorespiratory Fitness in Mid-Childhood: The PANIC Study. Sports Med 2017; 47:769–780.

Haapala EA, Eloranta A-M, Venalainen T, Jalkanen H, Poikkeus A-M, Ahonen T, Lindi V, Lakka TA. Diet quality and academic achievement: a prospective study among primary school children. Eur J.Nutr 2017; 56:2299-2308. doi: 10.1007/s00394-016-1270-5.

Vierola A, Suominen AL, Eloranta A-M, Lintu N, Ikävalko T, Närhi M, Lakka TA. Determinants for craniofacial pains in children 6-8 years of age: the PANIC study. Acta Odontol Scand 2017;75(6):453–460.

Määttä S, Könönen M, Kallioniemi E, Lakka T, Lintu N, Lindi V, Ferreri F, Ponzo D, Säisänen L. Development of cortical motor circuits between childhood and adulthood: a navigated TMS-HdEEG study. Hum Brain Mapp 2017; 38:2599-2615.

Jalkanen H, Lindi V, Schwab U, Kiiskinen S, Venäläinen T, Karhunen L, Lakka TA, Eloranta AM. Eating behaviour is associated with eating frequency and food consumption in 6-8  year-old children: The Physical Activity and Nutrition in Children (PANIC) study. Appetite 2017;114:28–37. doi: 10.1016/j.appet.2017.03.011.

Haapala EA, Väistö J, Veijalainen A, Lintu N, Wiklund P, Westgate K, Ekelund U, Lindi V, Brage S, Lakka TA. Associations of objectively measured physical activity and sedentary time with arterial stiffness in pre-pubertal children. Pediatr Exerc Sci 2017;29:326-335. Available from: http://journals.humankinetics.com/doi/10.1123/pes.2016-0168

Lampinen EK, Eloranta AM, Haapala EA, Lindi V, Väistö J, Lintu N, Karjalainen P, Kukkonen-Harjula K, Laaksonen D, Lakka TA. Physical activity, sedentary behaviour, and socioeconomic status among Finnish girls and boys aged 6–8 years. Eur. J. Sport Sci. 2017;17(4):462–72.

Haapala EA, Väistö J, Lintu N, Westgate K, Ekelund U, Poikkeus AM, Brage S, Lakka TA. Physical activity and sedentary time in relation to academic achievement in children. J Sci Med Sport 2017;20:583-589. doi: 10.1016/j.jsams.2016.11.003.

Haapala EA, Väistö J, Lintu N, Eloranta A-M, Lindi V, Lakka TA. Vähäinen fyysinen aktiivisuus ja runsas fyysinen passiivisuus ovat yhteydessä 6-8-vuotiaiden lasten ylipainoon. Liikunta ja tiede 2017;54(2-3):106-112.

2016

Venalainen T, Agren J, Schwab U, de Mello VD, Eloranta A-M, Laaksonen DE, Lindi V, Lakka TA. Cross-sectional associations of plasma fatty acid composition and estimated desaturase and elongase activities with cardiometabolic risk in Finnish children–The PANIC study. J. Clin. Lipidol. 2016;10(1):82–91.

Viitasalo A, Agren J, Venalainen T, Pihlajamaki J, Jaaskelainen J, Korkmaz A, Atalay M, Lakka TA. Association of plasma fatty acid composition with plasma irisin levels in normal  weight and overweight/obese children. Pediatr. Obes. 2016 Aug;11(4):299–305.

Venalainen TM, Viitasalo AM, Schwab US, Eloranta A-M, Haapala EA, Jalkanen HP, de Mello VD, Laaksonen DE, Lindi VI, Agren JJ, Lakka TA. Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. Am. J. Clin. Nutr. 2016 Oct;104(4):964–72.

Aarela L, Nurminen S, Kivela L, Huhtala H, Maki M, Viitasalo A, Kaukinen K, Lakka T, Kurppa K. Prevalence and associated factors of abnormal liver values in children with celiac disease. Dig. Liver Dis. 2016 Sep;48(9):1023–9.

Lintu N, Savonen K, Viitasalo A, Tompuri T, Paananen J, Tarvainen MP, Lakka T. Determinants of Cardiorespiratory Fitness in a Population Sample of Girls and Boys Aged 6 to 8 Years. J. Phys. Act. Health.  2016 Nov;13(11):1149–55.

Felix JF, Bradfield JP, Monnereau C, van der Valk RJP, Stergiakouli E, Chesi A, Gaillard R, Feenstra B, Thiering E, Kreiner-Moller E, Mahajan A, Pitkanen N, Joro R, Cavadino A, Huikari V, Franks S, Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimaki T, Curtin JA, Vioque J, Ahluwalia TS, Myhre R, Price TS, Vilor-Tejedor N, Yengo L, Grarup N, Ntalla I, Ang W, Atalay M, Bisgaard H, Blakemore AI, Bonnefond A, Carstensen L, Eriksson J, Flexeder C, Franke L, Geller F, Geserick M, Hartikainen A-L, Haworth CMA, Hirschhorn JN, Hofman A, Holm J-C, Horikoshi M, Hottenga JJ, Huang J, Kadarmideen HN, Kahonen M, Kiess W, Lakka H-M, Lakka TA, Lewin AM, Liang L, Lyytikainen L-P, Ma B, Magnus P, McCormack SE, McMahon G, Mentch FD, Middeldorp CM, Murray CS, Pahkala K, Pers TH, Pfaffle R, Postma DS, Power C, Simpson A, Sengpiel V, Tiesler CMT, Torrent M, Uitterlinden AG, van Meurs JB, Vinding R, Waage J, Wardle J, Zeggini E, Zemel BS, Dedoussis G V, Pedersen O, Froguel P, Sunyer J, Plomin R, Jacobsson B, Hansen T, Gonzalez JR, Custovic A, Raitakari OT, Pennell CE, Widen E, Boomsma DI, Koppelman GH, Sebert S, Jarvelin M-R, Hypponen E, McCarthy MI, Lindi V, Harri N, Korner A, Bonnelykke K, Heinrich J, Melbye M, Rivadeneira F, Hakonarson H, Ring SM, Smith GD, Sorensen TIA, Timpson NJ, Grant SFA, Jaddoe VW V. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum. Mol. Genet. 2016 Jan;25(2):389–403.

Tompuri TT, Lintu N, Soininen S, Laitinen T, Lakka TA. Comparison between parameters from maximal cycle ergometer test first without respiratory gas analysis and thereafter with respiratory gas analysis among healthy prepubertal children. Appl. Physiol. Nutr. Metab. 2016 Jun;41(6):624–30.

Soininen S, Eloranta A-M, Lindi V, Venalainen T, Zaproudina N, Mahonen A, Lakka TA. Determinants of serum 25-hydroxyvitamin D concentration in Finnish children: the  Physical Activity and Nutrition in Children (PANIC) study. Br. J. Nutr. 2016 Mar;115(6):1080–91.

Veijalainen A, Tompuri T, Haapala EA, Viitasalo A, Lintu N, Vaisto J, Laitinen T, Lindi V, Lakka TA. Associations of cardiorespiratory fitness, physical activity, and adiposity with  arterial stiffness in children. Scand. J. Med. Sci. Sports. 2016 Aug;26(8):943–50.

Eloranta AM, Schwab U, Venalainen T, Kiiskinen S, Lakka HM, Laaksonen DE, Lakka TA, Lindi V. Dietary quality indices in relation to cardiometabolic risk among Finnish children aged 6-8 years – The PANIC study. Nutr. Metab. Cardiovasc. Dis. 2016 Sep;26(9):833–41.

Zaproudina N, Narhi M, Veijalainen A, Laitinen T, Lakka TA. Finger skin temperatures in 8- to 11-year-old children: determinants including physical characteristics and seasonal variation. The Physical Activity and Nutrition in Children (PANIC) Study. Eur. J. Appl. Physiol. 2016 Feb;116(2):405–13.

Viitasalo A, Pihlajamaki J, Paananen J, Atalay M, Lindi V, Lakka TA. Associations of TM6SF2 167K allele with liver enzymes and lipid profile in children: the PANIC Study. Pediatr. Res. 2016; 79(5):684–8.

Haapala EA, Viitasalo A, Venalainen T, Eloranta A-M, Agren J, Lindi V, Lakka TA. Plasma polyunsaturated fatty acids are directly associated with cognition in overweight children but not in normal weight children. Acta Paediatr. 2016 Dec;105(12):1502–7.

Eskeli R, Losonen M, Ikavalko T, Myllykangas R, Lakka T, Laine-Alava MT. Secular trends affect timing of emergence of permanent teeth. Angle Orthod. 2016 Jan;86(1):53–8.

Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikainen L-P, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Hottenga J-J, Vilor-Tejedor N, Joshi PK, Boh ETH, Ntalla I, Pitkanen N, Mahajan A, van Leeuwen EM, Joro R, Lagou V, Nodzenski M, Diver LA, Zondervan KT, Bustamante M, Marques-Vidal P, Mercader JM, Bennett AJ, Rahmioglu N, Nyholt DR, Ma RCW, Tam CHT, Tam WH, Ganesh SK, van Rooij FJ, Jones SE, Loh P-R, Ruth KS, Tuke MA, Tyrrell J, Wood AR, Yaghootkar H, Scholtens DM, Paternoster L, Prokopenko I, Kovacs P, Atalay M, Willems SM, Panoutsopoulou K, Wang X, Carstensen L, Geller F, Schraut KE, Murcia M, van Beijsterveldt CE, Willemsen G, Appel EVR, Fonvig CE, Trier C, Tiesler CM, Standl M, Kutalik Z, Bonas-Guarch S, Hougaard DM, Sanchez F, Torrents D, Waage J, Hollegaard M V, de Haan HG, Rosendaal FR, Medina-Gomez C, Ring SM, Hemani G, McMahon G, Robertson NR, Groves CJ, Langenberg C, Luan J, Scott RA, Zhao JH, Mentch FD, MacKenzie SM, Reynolds RM, Lowe WLJ, Tonjes A, Stumvoll M, Lindi V, Lakka TA, van Duijn CM, Kiess W, Korner A, Sorensen TI, Niinikoski H, Pahkala K, Raitakari OT, Zeggini E, Dedoussis G V, Teo Y-Y, Saw S-M, Melbye M, Campbell H, Wilson JF, Vrijheid M, de Geus EJ, Boomsma DI, Kadarmideen HN, Holm J-C, Hansen T, Sebert S, Hattersley AT, Beilin LJ, Newnham JP, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widen EE, Kahonen M, Viikari JS, Lehtimaki T, Vollenweider P, Bonnelykke K, Bisgaard H, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, Pisinger C, Pedersen O, Power C, Hypponen E, Wareham NJ, Hakonarson H, Davies E, Walker BR, Jaddoe VW, Jarvelin M-R, Grant SF, Vaag AA, Lawlor DA, Frayling TM, Davey Smith G, Morris AP, Ong KK, Felix JF, Timpson NJ, Perry JR, Evans DM, McCarthy MI, Freathy RM. Genome-wide associations for birth weight and correlations with adult disease. Nature 2016 Oct;538(7624):248–52.

Soininen S, Eloranta A-M, Lindi V, Lakka TA. Response: food fortification as a means to increase vitamin D intake. Br. J. Nutr. 2016 Sep;116(6):1134–5.

Eloranta A-M, Venalainen T, Soininen S, Jalkanen H, Kiiskinen S, Schwab U, Lakka TA, Lindi V. Food sources of energy and nutrients in Finnish girls and boys 6-8 years of age – the PANIC study. Food Nutr. Res.  2016;60:32444.

Viitasalo A, Eloranta A-M, Atalay M, Romeo S, Pihlajamaki J, Lakka TA. Association of MBOAT7 gene variant with plasma ALT levels in children: the PANIC  study. Pediatr. Res. 2016 Nov;80(5):651–5.

Haapala EA, Väistö J, Lintu N, Tompuri T, Brage S, Westgate K, Ekelund U, Lampinen E-K, Sääkslahti A, Lindi V, Lakka TA, Haapala EA, Väistö J, Lintu N, Tompuri T, Brage S, Westgate K, Ekelund U, Lampinen EK, Sääkslahti A, Lindi V LT. Adiposity, physical activity and neuromuscular performance in children. J. Sports Sci. [Internet]. 2016;414(January):1–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26734777

Vierola A, Suominen AL, Lindi V, Viitasalo A, Ikävalko T, Lintu N, Väistö J, Kellokoski J, Närhi M, Lakka TA. Associations of Sedentary Behavior, Physical Activity, Cardiorespiratory Fitness, and Body Fat Content with Pain Conditions in Children: The Physical Activity and Nutrition in Children Study. J. Pain. 2016;17(7):845–53.

Viitasalo A, Eloranta A-M, Lintu N, Väistö J, Venäläinen T, Kiiskinen S, Karjalainen P, Peltola J, Lampinen E-K, Haapala EA, Paananen J, Schwab U, Lindi V, Lakka TA. The Effects of a 2-year Individualized and Family-based Lifestyle Intervention on Physical Activity, Sedentary Behavior and Diet in Children. Prev. Med. (Baltim). [Internet]. 2016 Feb 22 [cited 2016 Feb 29];87:81–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26915641

Länsimies H, Halkoaho A, Pietilä A-M, Lintu N, Kangasniemi M, Eloranta A-M, Viitasalo A, Lakka TA. Is there a duty to participate in a health research? – A viewpoint of children 6-8 years of age and their parents. Int Diabetes Nurs 2016. doi: 10.1080/20573316.2016.1274170.

2015

Haapala EA, Eloranta A-M, Venalainen T, Schwab U, Lindi V, Lakka TA. Associations of diet quality with cognition in children – the Physical Activity and Nutrition in Children Study. Br. J. Nutr. 2015 Oct;114(7):1080–7.

van der Valk RJP, Kreiner-Moller E, Kooijman MN, Guxens M, Stergiakouli E, Saaf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Korner A, Thiering E, Curtin JA, Myhre R, Huikari V, Joro R, Kerkhof M, Warrington NM, Pitkanen N, Ntalla I, Horikoshi M, Veijola R, Freathy RM, Teo Y-Y, Barton SJ, Evans DM, Kemp JP, St Pourcain B, Ring SM, Davey Smith G, Bergstrom A, Kull I, Hakonarson H, Mentch FD, Bisgaard H, Chawes B, Stokholm J, Waage J, Eriksen P, Sevelsted A, Melbye M, van Duijn CM, Medina-Gomez C, Hofman A, de Jongste JC, Taal HR, Uitterlinden AG, Armstrong LL, Eriksson J, Palotie A, Bustamante M, Estivill X, Gonzalez JR, Llop S, Kiess W, Mahajan A, Flexeder C, Tiesler CMT, Murray CS, Simpson A, Magnus P, Sengpiel V, Hartikainen A-L, Keinanen-Kiukaanniemi S, Lewin A, Da Silva Couto Alves A, Blakemore AI, Buxton JL, Kaakinen M, Rodriguez A, Sebert S, Vaarasmaki M, Lakka T, Lindi V, Gehring U, Postma DS, Ang W, Newnham JP, Lyytikainen L-P, Pahkala K, Raitakari OT, Panoutsopoulou K, Zeggini E, Boomsma DI, Groen-Blokhuis M, Ilonen J, Franke L, Hirschhorn JN, Pers TH, Liang L, Huang J, Hocher B, Knip M, Saw S-M, Holloway JW, Melen E, Grant SFA, Feenstra B, Lowe WL, Widen E, Sergeyev E, Grallert H, Custovic A, Jacobsson B, Jarvelin M-R, Atalay M, Koppelman GH, Pennell CE, Niinikoski H, Dedoussis G V, Mccarthy MI, Frayling TM, Sunyer J, Timpson NJ, Rivadeneira F, Bonnelykke K, Jaddoe VW V. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum. Mol. Genet. 2015 Feb;24(4):1155–68.

Viitasalo A, Pihlajamaki J, Lindi V, Atalay M, Kaminska D, Joro R, Lakka TA. Associations of I148M variant in PNPLA3 gene with plasma ALT levels during 2-year follow-up in normal weight and overweight children: the PANIC Study. Pediatr. Obes. 2015 Apr;10(2):84–90.

Qi Q, Downer MK, Kilpeläinen TO, Rob Taal H, Barton SJ, Ntalla I, Standl M, Boraska V, Huikari V, Kiefte-de Jong JC, Körner A, Lakka TA, Liu G, Magnusson J, Okuda M, Raitakari O, Richmond R, Scott RA, Bailey MES, Scheuermann K, Holloway JW, Inskip H, Isasi CR, Mossavar-Rahmani Y, Jaddoe VWV, Laitinen J, Lindi V, Melén E,Pitsiladis Y, Pitkänen N, Snieder H, Heinrich J, Timpson NJ, Wang T, Yuji H, Zeggini E, Dedoussis GV, Kaplan RC, Wylie-Rosett J, Loos RJF, Hu FB, Qi L. Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents. Diabetes 2015;64:2467-2476. doi: 10.2337/db14-1629.

Ikavalko T, Narhi M, Lakka T, Myllykangas R, Tuomilehto H, Vierola A, Pahkala R. Lateral facial profile may reveal the risk for sleep disordered breathing in children–the PANIC-study. Acta Odontol. Scand.  2015;73(7):550–5.

Qi Q, Downer MK, Kilpelainen TO, Taal HR, Barton SJ, Ntalla I, Standl M, Boraska V, Huikari V, Kiefte-de Jong JC, Korner A, Lakka TA, Liu G, Magnusson J, Okuda M, Raitakari O, Richmond R, Scott RA, Bailey MES, Scheuermann K, Holloway JW, Inskip H, Isasi CR, Mossavar-Rahmani Y, Jaddoe VW V, Laitinen J, Lindi V, Melen E, Pitsiladis Y, Pitkanen N, Snieder H, Heinrich J, Timpson NJ, Wang T, Yuji H, Zeggini E, Dedoussis G V, Kaplan RC, Wylie-Rosett J, Loos RJF, Hu FB, Qi L. Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over  16,000 Children and Adolescents. Diabetes. 2015 Jul;64(7):2467–76.

Viitasalo A, Atalay M, Pihlajamaki J, Jaaskelainen J, Korkmaz A, Kaminska D, Lindi V, Lakka TA. The 148 M allele of the PNPLA3 is associated with plasma irisin levels in a population sample of Caucasian children: The PANIC Study. Metabolism. 2015 Jul;64(7):793–6.

Tompuri T, Lintu N, Savonen K, Laitinen T, Laaksonen D, Jaaskelainen J, Lakka TA. Measures of cardiorespiratory fitness in relation to measures of body size and composition among children. Clin. Physiol. Funct. Imaging. 2015 Nov;35(6):469–77.

Tompuri TT, Lakka TA, Hakulinen M, Lindi V, Laaksonen DE, Kilpeläinen TO, Jääskeläinen J, Lakka H-M, Laitinen T. Assessment of body composition by dual-energy X-ray absorptiometry, bioimpedance analysis and anthropometrics in children: the Physical Activity and Nutrition in Children study. Clin. Physiol. Funct. Imaging [Internet]. 2015 Jan [cited 2017 Oct 17];35(1):21–33. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24325400

Haapala EA, Lintu N, Väistö J, Robinson LE, Viitasalo A, Lindi V, Lakka TA. Associations of physical performance and adiposity with cognition in children. Med. Sci. Sport. Exerc. [Internet]. 2015;47(10):2166–74. Available from: http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00005768-201510000-00019

Lintu N, Viitasalo A, Tompuri T, Veijalainen A, Hakulinen M, Laitinen T, Savonen K, Lakka TA. Cardiorespiratory fitness, respiratory function and hemodynamic responses to maximal cycle ergometer exercise test in girls and boys aged 9-11 years: the PANIC Study. Eur. J. Appl. Physiol. [Internet]. 2015 Feb [cited 2016 Mar 24];115(2):235–43. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25272972

2014

Mantyselka A, Jaaskelainen J, Lindi V, Viitasalo A, Tompuri T, Voutilainen R, Lakka TA. The presentation of adrenarche is sexually dimorphic and modified by body adiposity. J. Clin. Endocrinol. Metab. 2014 Oct;99(10):3889–94.

Viitasalo A, Lakka TA, Laaksonen DE, Savonen K, Lakka H-M, Hassinen M, Komulainen P, Tompuri T, Kurl S, Laukkanen JA, Rauramaa R. Validation of metabolic syndrome score by confirmatory factor analysis in children and adults and prediction of cardiometabolic outcomes in adults. Diabetologia. 2014 May;57(5):940–9.

Seppala S, Laitinen T, Tarvainen MP, Tompuri T, Veijalainen A, Savonen K, Lakka T. Normal values for heart rate variability parameters in children 6-8 years of age: the PANIC Study. Clin. Physiol. Funct. Imaging. 2014 Jul;34(4):290–6.

Venalainen T, Schwab U, Agren J, de Mello V, Lindi V, Eloranta A-M, Kiiskinen S, Laaksonen D, Lakka TA. Cross-sectional associations of food consumption with plasma fatty acid composition and estimated desaturase activities in Finnish children. Lipids. 2014 May;49(5):467–79.

Eloranta AM, Lindi V, Schwab U, Kiiskinen S, Venalainen T, Lakka HM, Laaksonen DE, Lakka TA. Dietary factors associated with metabolic risk score in Finnish children aged 6-8 years: the PANIC study. Eur. J. Nutr. 2014 Sep;53(6):1431–9.

Cousminer DL, Stergiakouli E, Berry DJ, Ang W, Groen-Blokhuis MM, Korner A, Siitonen N, Ntalla I, Marinelli M, Perry JRB, Kettunen J, Jansen R, Surakka I, Timpson NJ, Ring S, Mcmahon G, Power C, Wang C, Kahonen M, Viikari J, Lehtimaki T, Middeldorp CM, Hulshoff Pol HE, Neef M, Weise S, Pahkala K, Niinikoski H, Zeggini E, Panoutsopoulou K, Bustamante M, Penninx BWJH, Murabito J, Torrent M, Dedoussis G V, Kiess W, Boomsma DI, Pennell CE, Raitakari OT, Hypponen E, Davey Smith G, Ripatti S, McCarthy MI, Widen E. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Hum. Mol. Genet. 2014 Aug;23(16):4452–64.

Väistö J, Eloranta A-M, Viitasalo A, Tompuri T, Lintu N, Karjalainen P, Lampinen E-K, Agren J, Laaksonen DE, Lakka H-M, Lindi V, Lakka TA. Physical activity and sedentary behaviour in relation to cardiometabolic risk in children: cross-sectional findings from the Physical Activity and Nutrition in Children (PANIC) Study. Int. J. Behav. Nutr. Phys. Act. 2014;11(1):55. doi: 10.1186/1479-5868-11-55.

Haapala EA, Poikkeus A-M, Tompuri T, Kukkonen-Harjula K, Leppanen PHT, Lindi V, Lakka TA. Associations of motor and cardiovascular performance with academic skills in children. Med. Sci. Sports Exerc.  2014;46(5):1016–24.

Haapala E a, Poikkeus A-M, Kukkonen-Harjula K, Tompuri T, Lintu N, Väistö J, Leppänen PHT, Laaksonen DE, Lindi V, Lakka T a. Associations of physical activity and sedentary behavior with academic skills–a follow-up study among primary school children. PLoS One [Internet]. 2014;9(9):e107031. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4160223&tool=pmcentrez&rendertype=abstract

Lintu N, Tompuri T, Viitasalo A, Soininen S, Laitinen T, Savonen K, Lindi V, Lakka TA. Cardiovascular fitness and haemodynamic responses to maximal cycle ergometer exercise test in children 6-8 years of age. J. Sports Sci. [Internet]. 2014 Jan [cited 2016 Mar 24];32(7):652–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24279412

2013

Valtonen M, Heinonen OJ, Lakka TA, Tammelin T. Significance of physical activity in childhood – a cardiometabolic view. Duodecim. 2013;129(11):1153–8.

Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Byrne EM, Taal HR, Huikari V, Bradfield JP, Kerkhof M, Groen-Blokhuis MM, Kreiner-Moller E, Marinelli M, Holst C, Leinonen JT, Perry JRB, Surakka I, Pietilainen O, Kettunen J, Anttila V, Kaakinen M, Sovio U, Pouta A, Das S, Lagou V, Power C, Prokopenko I, Evans DM, Kemp JP, St Pourcain B, Ring S, Palotie A, Kajantie E, Osmond C, Lehtimaki T, Viikari JS, Kahonen M, Warrington NM, Lye SJ, Palmer LJ, Tiesler CMT, Flexeder C, Montgomery GW, Medland SE, Hofman A, Hakonarson H, Guxens M, Bartels M, Salomaa V, Murabito JM, Kaprio J, Sorensen TIA, Ballester F, Bisgaard H, Boomsma DI, Koppelman GH, Grant SFA, Jaddoe VW V, Martin NG, Heinrich J, Pennell CE, Raitakari OT, Eriksson JG, Smith GD, Hypponen E, Jarvelin M-R, McCarthy MI, Ripatti S, Widen E. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Hum. Mol. Genet. 2013 Jul;22(13):2735–47.

Veijalainen A, Tompuri T, Laitinen T, Lintu N, Viitasalo A, Laaksonen DE, Jaaskelainen J, Lakka TA. Metabolic risk factors are associated with stiffness index, reflection index and  finger skin temperature in children–Physical Activity and Nutrition in Children (PANIC) study. Circ. J. 2013;77(5):1281–8.

Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimaki T, Kreiner-Moller E, Warrington NM, Bustamante M, Feenstra B, Berry DJ, Thiering E, Pfab T, Barton SJ, Shields BM, Kerkhof M, van Leeuwen EM, Fulford AJ, Kutalik Z, Zhao JH, den Hoed M, Mahajan A, Lindi V, Goh L-K, Hottenga J-J, Wu Y, Raitakari OT, Harder MN, Meirhaeghe A, Ntalla I, Salem RM, Jameson KA, Zhou K, Monies DM, Lagou V, Kirin M, Heikkinen J, Adair LS, Alkuraya FS, Al-Odaib A, Amouyel P, Andersson EA, Bennett AJ, Blakemore AIF, Buxton JL, Dallongeville J, Das S, de Geus EJC, Estivill X, Flexeder C, Froguel P, Geller F, Godfrey KM, Gottrand F, Groves CJ, Hansen T, Hirschhorn JN, Hofman A, Hollegaard M V, Hougaard DM, Hypponen E, Inskip HM, Isaacs A, Jorgensen T, Kanaka-Gantenbein C, Kemp JP, Kiess W, Kilpelainen TO, Klopp N, Knight BA, Kuzawa CW, McMahon G, Newnham JP, Niinikoski H, Oostra BA, Pedersen L, Postma DS, Ring SM, Rivadeneira F, Robertson NR, Sebert S, Simell O, Slowinski T, Tiesler CMT, Tonjes A, Vaag A, Viikari JS, Vink JM, Vissing NH, Wareham NJ, Willemsen G, Witte DR, Zhang H, Zhao J, Wilson JF, Stumvoll M, Prentice AM, Meyer BF, Pearson ER, Boreham CAG, Cooper C, Gillman MW, Dedoussis G V, Moreno LA, Pedersen O, Saarinen M, Mohlke KL, Boomsma DI, Saw S-M, Lakka TA, Korner A, Loos RJF, Ong KK, Vollenweider P, van Duijn CM, Koppelman GH, Hattersley AT, Holloway JW, Hocher B, Heinrich J, Power C, Melbye M, Guxens M, Pennell CE, Bonnelykke K, Bisgaard H, Eriksson JG, Widen E, Hakonarson H, Uitterlinden AG, Pouta A, Lawlor DA, Smith GD, Frayling TM, McCarthy MI, Grant SFA, Jaddoe VW V, Jarvelin M-R, Timpson NJ, Prokopenko I, Freathy RM. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat. Genet. 2013 Jan;45(1):76–82.

2012

Vierola A, Suominen AL, Ikavalko T, Lintu N, Lindi V, Lakka H-M, Kellokoski J, Narhi M, Lakka TA. Clinical signs of temporomandibular disorders and various pain conditions among children 6 to 8 years of age: the PANIC study. J. Orofac. Pain. 2012;26(1):17–25.

Taal HR, Pourcain BS, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Moller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bonnelykke K, Buxton JL, Charoen P, Chawes BLK, Eriksson J, Evans DM, Hofman A, Kemp JP, Kim CE, Klopp N, Lahti J, Lye SJ, McMahon G, Mentch FD, Muller M, O’Reilly PF, Prokopenko I, Rivadeneira F, Steegers EAP, Sunyer J, Tiesler C, Yaghootkar H, Breteler MMB, Debette S, Fornage M, Gudnason V, Launer LJ, van der Lugt A, Mosley TH, Seshadri S, Smith A V, Vernooij MW, Blakemore AI, Chiavacci RM, Feenstra B, Fernandez-Benet J, Grant SFA, Hartikainen A-L, van der Heijden AJ, Iniguez C, Lathrop M, McArdle WL, Molgaard A, Newnham JP, Palmer LJ, Palotie A, Pouta A, Ring SM, Sovio U, Standl M, Uitterlinden AG, Wichmann H-E, Vissing NH, DeCarli C, van Duijn CM, McCarthy MI, Koppelman GH, Estivill X, Hattersley AT, Melbye M, Bisgaard H, Pennell CE, Widen E, Hakonarson H, Smith GD, Heinrich J, Jarvelin M-R, Jaddoe VW V. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nat. Genet. 2012 Apr;44(5):532–8.

Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PMA, Zhao J, Berkowitz RI, Vimaleswaran KS, Jarick I, Pennell CE, Evans DM, St Pourcain B, Berry DJ, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, van der Valk RJP, de Jongste JC, Postma DS, Boomsma DI, Gauderman WJ, Hassanein MT, Lindgren CM, Magi R, Boreham CAG, Neville CE, Moreno LA, Elliott P, Pouta A, Hartikainen A-L, Li M, Raitakari O, Lehtimaki T, Eriksson JG, Palotie A, Dallongeville J, Das S, Deloukas P, McMahon G, Ring SM, Kemp JP, Buxton JL, Blakemore AIF, Bustamante M, Guxens M, Hirschhorn JN, Gillman MW, Kreiner-Moller E, Bisgaard H, Gilliland FD, Heinrich J, Wheeler E, Barroso I, O’Rahilly S, Meirhaeghe A, Sorensen TIA, Power C, Palmer LJ, Hinney A, Widen E, Farooqi IS, McCarthy MI, Froguel P, Meyre D, Hebebrand J, Jarvelin M-R, Jaddoe VW V, Smith GD, Hakonarson H, Grant SFA. A genome-wide association meta-analysis identifies new childhood obesity loci. Nat. Genet. 2012 May;44(5):526–31.

Ikram MA, Fornage M, Smith A V, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WTJ, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CRJ, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen A-L, Pennell CE, Thiering E, Steegers EAP, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin M-R, McCarthy MI, Grant SFA, St Pourcain B, Timpson NJ, Smith GD, Sovio U, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW V, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley THJ, Schmidt H, Launer LJ, Breteler MMB, DeCarli C. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat. Genet. 2012 Apr;44(5):539–44.

Ikavalko T, Tuomilehto H, Pahkala R, Tompuri T, Laitinen T, Myllykangas R, Vierola A, Lindi V, Narhi M, Lakka TA. Craniofacial morphology but not excess body fat is associated with risk of having sleep-disordered breathing–the PANIC Study (a questionnaire-based inquiry in 6-8-year-olds). Eur. J. Pediatr. 2012 Dec;171(12):1747–52.

Viitasalo A, Laaksonen DE, Lindi V, Eloranta A-M, Jääskeläinen J, Tompuri T, Väisänen S, Lakka H-M, Lakka TA. Clustering of metabolic risk factors is associated with high-normal levels of liver enzymes among 6- to 8-year-old children: the PANIC study. Metab. Syndr. Relat. Disord. [Internet]. 2012 Oct [cited 2015 Oct 30];10(5):337–43. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22731985

Eloranta A-M, Lindi V, Schwab U, Tompuri T, Kiiskinen S, Lakka H-M, Laitinen T, Lakka TA. Dietary factors associated with overweight and body adiposity in Finnish children aged 6-8 years: the PANIC Study. Int. J. Obes. (Lond). [Internet]. 2012 Jul [cited 2015 Oct 30];36(7):950–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22665136

2011

Kilpelainen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, Ahmad T, Mora S, Kaakinen M, Sandholt CH, Holzapfel C, Autenrieth CS, Hypponen E, Cauchi S, He M, Kutalik Z, Kumari M, Stancakova A, Meidtner K, Balkau B, Tan JT, Mangino M, Timpson NJ, Song Y, Zillikens MC, Jablonski KA, Garcia ME, Johansson S, Bragg-Gresham JL, Wu Y, van Vliet-Ostaptchouk J V, Onland-Moret NC, Zimmermann E, Rivera N V, Tanaka T, Stringham HM, Silbernagel G, Kanoni S, Feitosa MF, Snitker S, Ruiz JR, Metter J, Larrad MTM, Atalay M, Hakanen M, Amin N, Cavalcanti-Proenca C, Grontved A, Hallmans G, Jansson J-O, Kuusisto J, Kahonen M, Lutsey PL, Nolan JJ, Palla L, Pedersen O, Perusse L, Renstrom F, Scott RA, Shungin D, Sovio U, Tammelin TH, Ronnemaa T, Lakka TA, Uusitupa M, Rios MS, Ferrucci L, Bouchard C, Meirhaeghe A, Fu M, Walker M, Borecki IB, Dedoussis G V, Fritsche A, Ohlsson C, Boehnke M, Bandinelli S, van Duijn CM, Ebrahim S, Lawlor DA, Gudnason V, Harris TB, Sorensen TIA, Mohlke KL, Hofman A, Uitterlinden AG, Tuomilehto J, Lehtimaki T, Raitakari O, Isomaa B, Njolstad PR, Florez JC, Liu S, Ness A, Spector TD, Tai ES, Froguel P, Boeing H, Laakso M, Marmot M, Bergmann S, Power C, Khaw K-T, Chasman D, Ridker P, Hansen T, Monda KL, Illig T, Jarvelin M-R, Wareham NJ, Hu FB, Groop LC, Orho-Melander M, Ekelund U, Franks PW, Loos RJF. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med. 2011 Nov;8(11):e1001116.

Veijalainen A, Tompuri T, Lakka H-M, Laitinen T, Lakka TA. Reproducibility of pulse contour analysis in children before and after maximal exercise stress test: the Physical Activity and Nutrition in Children (PANIC) study. Clin. Physiol. Funct. Imaging. 2011 Mar;31(2):132–8.

Eloranta AM, Lindi V, Schwab U, Kiiskinen S, Kalinkin M, Lakka HM, Lakka TA. Dietary factors and their associations with socioeconomic background in Finnish girls and boys 6-8 years of age: the PANIC Study. Eur. J. Clin. Nutr. 2011 Nov;65(11):1211–8.